Methods of Protein Digestive Stability Assay – State of the Art

The evaluation of protein stability in digestive tract is an important topic in various fields of biomedical sciences. The most straightforward task within it is the evaluation of food quality, as during the food processing the digestibility of a protein could fall dramatically. Another task, tightly connected with the previous one, is the evaluation of protein allergenicity. This parameter is shown to be dependent on protein’s digestibility, the less digestible ones having the highest probability to induce immune response. Finally, the task of development of new peptide drugs also requires digestive stability check for per os drug forms that are the most convenient for a patient.